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Index > Protein center > CCK(Gene name) > Dog
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  • CCK (Gene name),
  • Cholecystokinins (Protein name ),  CCKN_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CCK;
    Protein name:
    Cholecystokinins(CCK);
    Alternative:

    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    Binds to CCK-A receptors in the pancreas and CCK-B receptors in the brain. cholecystokinin 8 binds CCK-A receptors more potently than cholecystokinin 58, cholecystokinin 8 and cholecystokinin 58 bind CCK-B receptors with equal affinity.
    Function:
    This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. cholecystokinin 58 and cholecystokinin 8, but not cholecystokinin 58 desnonopeptide, stimulate amylase release from the pancreas. cholecystokinin 58, but not cholecystokinin 8, increases bile-pancreatic volume.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    58
    Sequence:
    50:
    AVQKVDGEPR | AHLGALLARY | IQQARKAPSG | RMSVIKNLQN | LDPSHRISDR | 
    58:
    DYMGWMDF
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Dog CCK
    Cat.:
    E0802r
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    96T
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    ELISA Kit for Dog CCK
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    E0802h
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    96T
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    ELISA Kit for Dog CCK
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    E0802p
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    96T
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    ELISA Kit for Dog CCK
    Cat.:
    E0802c
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    96T
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    ELISA Kit for Dog CCK
    Cat.:
    E0802b
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    Packing:
    96T
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    ELISA Kit for Dog CCK
    Cat.:
    E0802m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Dog CCK
    Cat.:
    E0802d
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    Packing:
    96T
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    CLIA Kit for Dog CCK
    MSDS:
    Please sign in first.
    CLIA Kit for Dog CCK
    Cat.:
    U0802p
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Dog CCK
    Cat.:
    U0802b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog CCK
    Cat.:
    U0802c
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog CCK
    Cat.:
    U0802h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Dog CCK
    Cat.:
    U0802m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog CCK
    Cat.:
    U0802r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Dog CCK
    Cat.:
    P0802Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog CCK
    Polyclonal Antibody for Dog CCK
    Cat.:
    P0802Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog CCK
    Polyclonal Antibody for Dog CCK
    Polyclonal Antibody for Dog CCK
    Polyclonal Antibody for Dog CCK
    Cat.:
    P0802Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Dog CCK
    Monoclonal Antibody for Dog CCK
    Monoclonal Antibody for Dog CCK
    Monoclonal Antibody for Dog CCK
    Monoclonal Antibody for Dog CCK
    Monoclonal Antibody for Dog CCK
    Monoclonal Antibody for Dog CCK
    Protein for Dog CCK
    Protein for Dog CCK
    Protein for Dog CCK
    Protein for Dog CCK
    Protein for Dog CCK
    Protein for Dog CCK
    Protein for Dog CCK
    Cat.:
    R0802h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%

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    References
    1. 1.
      "New molecular forms of cholecystokinin. Microsequence analysis of forms previously characterized by chromatographic methods."
      Reeve J.R. Jr. , Eysselein V.E. , Walsh J.H. , Ben-Avram C.M. , Shively J.E.
      J. Biol. Chem.261:16392-16397(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE
      strain: Mongrel.
      tissue: Intestinal mucosa.
    2. 2.
      "Partial structure of a large canine cholecystokinin (CCK58): amino acid sequence."
      Eysselein V.E. , Reeve J.R. Jr. , Shively J.E. , Hawke D. , Walsh J.H.
      Peptides3:687-691(1982) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-38;FUNCTION
      tissue: Intestinal mucosa.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-29;SYNTHESIS;FUNCTION;MASS SPECTROMETRY;SULFATION AT TYR-52
    4. 4.
      "Identification of nonsulfated cholecystokinin-58 in canine intestinal extracts and its biological properties."
      Reeve J.R. Jr. , Liddle R.A. , McVey D.C. , Vigna S.R. , Solomon T.E. , Keire D.A. , Rosenquist G. , Shively J.E. , Lee T.D. , Chew P. , Green G.M. , Coskun T.
      Am. J. Physiol.287:G326-G333(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-25 AND 32-58;FUNCTION;AMIDATION AT PHE-58;SULFATION AT TYR-52
      tissue: Intestinal mucosa.
    5. 5.
      "Isolation of a large cholecystokinin precursor from canine brain."
      Eysselein V.E. , Reeve J.R. Jr. , Shively J.E. , Miller C. , Walsh J.H.
      Proc. Natl. Acad. Sci. U.S.A.81:6565-6568(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-22
      strain: Mongrel.
      tissue: Brain.
    6. 6.
      "Characterization of canine intestinal cholecystokinin-58 lacking its carboxyl-terminal nonapeptide. Evidence for similar post-translational processing in brain and gut."
      Reeve J.R. Jr. , Eysselein V.E. , Eberlein G.A. , Chew P. , Ho F.-J. , Huebner V.D. , Shively J.E. , Lee T.D. , Liddle R.A.
      J. Biol. Chem.266:13770-13776(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-12;FUNCTION;MASS SPECTROMETRY
      strain: Mongrel.
      tissue: Intestinal mucosa.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SYNTHESIS OF 51-58;MASS SPECTROMETRY
    8. 8.
      "Differences in receptor binding and stability to enzymatic digestion between CCK-8 and CCK-58."
      Reeve J.R. Jr. , McVey D.C. , Bunnett N.W. , Solomon T.E. , Keire D.A. , Ho F.-J. , Davis M.T. , Lee T.D. , Shively J.E. , Vigna S.R.
      Pancreas25:E50-E55(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;MASS SPECTROMETRY
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